Micronutrient and nutritional deficiencies associated with GLP-1 agonist use 🚨
They help reduce food intake, but are you missing out on vital nutrients.
Micronutrient and Nutritional Deficiencies Associated With GLP-1 Receptor Agonist Therapy: A Narrative Review
Study Details
This new narrative review synthesised data from 6 studies (480,825 adults) to establish common deficient with GLP-1 receptor agonist (GLP-1RA) use 📚
Here are the key findings ⬇️
Key Findings
☀️ Vitamin D deficiency was most common, affecting 7.5% at 6 months and 13.6% at 12 months
🩸 Iron depletion was frequent, with GLP-1RA users showing 26% - 30% lower ferritin vs SGLT2 inhibitor users
🥛 Over 60% consumed below calcium and iron requirements, while vitamin D intake averaged ~20% of recommendations
💪 Low protein and calcium contributed to lean mass loss
🧠 Thiamine and cobalamin deficits increased over time
Conclusion
GLP-1RA therapy is linked with meaningful nutritional deficiencies‼️
Without adequate nutritional support, many patients simply “eat less” without awareness of the beneficial nutrients that can be missing from their diets 🧐
Which may have downstream effects for health and longevity ⚠️
Reference
https://pubmed.ncbi.nlm.nih.gov/41549912/
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