Nutritional supplements for knee osteoarthritis 💊
Which supplements actually work?
Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis
Study Details
This new meta-analysis compiled data from 39 studies (4599 patients) to establish the effectiveness of supplements for treating knee osteoarthritis (KOA) 📚
Supplements evaluated included…
🥚 Eggshell membrane
☀️ Vitamin D
🌿 Boswellia
💊 Curcumin
🫚 Ginger
🐟 Krill oil
💊 Collagen
Here is what they found ⬇️
Key Findings
Compared to placebo, Boswellia (≥ 100 mg/day) showed significant improvements in…
💥 WOMAC pain
🧱 Stiffness
🛠️ Function
📏 VAS pain
💊 Collagen (≥ 40 mg/day)
🫚 Ginger (≥ 30 mg/day)
🐟 Krill oil (≥ 300 mg/day)
💊 Curcumin (≥ 500 mg/day)
…also demonstrated benefits in some outcomes (symptoms and function) ✅
No supplement was associated with increased adverse events compared to placebo 👍
Bayesian rankings indicated…
🌿 Boswellia had the highest probability of being most effective for pain and stiffness
🐟💊 Krill oil and curcumin showing highest probability for function improvement
Conclusion
Nutritional supplements, particularly Boswellia, appear to be effective and well-tolerated for improving KOA symptoms and function ✅
These supplements may offer a non-pharmacological alternative for KOA management 🩺
However, more evidence is required to identify optimal dosing protocols 🔍
Reference
https://pubmed.ncbi.nlm.nih.gov/40806131/
Performance Nutrition Digest is powered by Healthspan Elite ⚡️
Healthspan Elite is a science-led sports nutrition range developed in collaboration with leading experts to support athletic performance, recovery, and health.
Use code: TCDIGEST25 for 25% off at https://www.healthspanelite.co.uk/ 💪