Probiotics significantly affect neurotransmitters 🧠

Similar to the effect of SSRIs.

Exploring neurotransmitter regulation following probiotic supplementation in adults with subthreshold depression: A secondary analysis of a randomized controlled trial

Study Details

This new double-blind study investigated the effects of a daily dose of either…

🧫 Probiotics (4 billion CFU)

💊 Placebo

…for 12-weeks on neurotransmitter changes in adults with subthreshold depression 🔍

Here is what they found ⬇️

Key Findings

Plasma serotonin concentrations significantly increased at 6 weeks in both probiotic and placebo groups🩸

But only in the placebo group at 12-weeks 📈

After 6-weeks an inverse regulation (leading to decreased plasma serotonin levels) was observed in the probiotic group 📉

Conclusion

These plasma serotonin changes observed in the probiotic group resemble the effect of SSRIs 🔬

Therefore, probiotics may be a safe and preventative option for severe depressive disorder development ✅

Reference

https://pubmed.ncbi.nlm.nih.gov/40729791/

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