Saffron extract improves subjective and objective sleep quality 😴
Flower power.
A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the gut-sleep-brain axis randomised, double-blind, placebo-controlled pilot study
Study Details
This new study recruited 52 healthy older adults with sleep complaints to receive 4-weeks of either…
🌸 Saffron (30 mg/day)
💊 Placebo
…to investigate effects on sleep quality assessed via questionnaires and electroencephalography (sleep tracking) ⌚️
A subgroup (n = 26) also had gut microbiota composition analysed 🔬
Here is what they found ⬇️
Key Findings
After 4-weeks supplementation the saffron group had significantly improved…
✅ Sleep quality
✅ Sleep efficiency
✅ Sleep onset latency
In the saffron group there were also significant changes in gut microbiota composition including increased…
👉 Oscillibacter
👉 UBA1819
Both of which produce short-chain fatty acids and in this study were…
📈 positively associated with subjective sleep efficiency
📉 inversely associated with sleep latency
Conclusion
Saffron supplementation can improve sleep in adults, this may be modulated in part by changes in gut microbiota composition 🧫
Potentially providing evidence to support the gut-sleep-brain axis ✅
Reference
https://pubmed.ncbi.nlm.nih.gov/40762630/
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